Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency, also known as lal deficiency, is related to cholesteryl ester storage disease and cholesterol ester storage disease, and has symptoms including diarrhea and vomiting. An important gene associated with Lysosomal Acid Lipase Deficiency is LIPA (Lipase A, Lysosomal Acid Type), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Cyclophosphamide and Busulfan have been mentioned in the context of this disorder. Affiliated tissues include liver and spleen, and related phenotypes are nausea and vomiting and cognitive impairment