Leptin Deficiency or Dysfunction (LEPD)

Leptin Deficiency or Dysfunction, also known as obesity due to congenital leptin deficiency, is related to prader-willi syndrome and metabolic dysfunction-associated steatotic liver disease, and has symptoms including obesity, metabolically benign An important gene associated with Leptin Deficiency or Dysfunction is LEP (Leptin), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Clomifene and Octreotide have been mentioned in the context of this disorder. Affiliated tissues include adipocyte and liver, and related phenotypes are obesity and decreased serum leptin.