Lambert-Eaton Myasthenic Syndrome (LEMS)

Lambert-Eaton Myasthenic Syndrome, also known as lambert-eaton syndrome, is related to small cell cancer of the lung and myasthenia gravis. An important gene associated with Lambert-Eaton Myasthenic Syndrome is CACNB2 (Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2), and among its related pathways/superpathways are ERK Signaling and MAPK signaling pathway. The drugs Racephedrine and Picropodophyllin have been mentioned in the context of this disorder. Affiliated tissues include lung and spinal cord, and related phenotypes are abnormal autonomic nervous system physiology and reduced tendon reflexes