Li-Fraumeni Syndrome 2 (LFS2)

Li-Fraumeni Syndrome 2, also known as li-fraumeni syndrome, is related to tumor predisposition syndrome 4 and bone osteosarcoma. An important gene associated with Li-Fraumeni Syndrome 2 is CHEK2 (Checkpoint Kinase 2). The drugs Benzocaine and Topotecan have been mentioned in the context of this disorder. Affiliated tissues include breast, and related phenotypes are glioma and meningioma