Lecithin:cholesterol Acyltransferase Deficiency (LCATD)

Lecithin:cholesterol Acyltransferase Deficiency, also known as norum disease, is related to fish-eye disease and metabolic dysfunction-associated steatotic liver disease. An important gene associated with Lecithin:cholesterol Acyltransferase Deficiency is LCAT (Lecithin-Cholesterol Acyltransferase), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Olfactory Signaling Pathway. The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include eye and kidney, and related phenotypes are hypertriglyceridemia and decreased hdl cholesterol concentration