Isolated Ectopia Lentis (IEL)

Isolated Ectopia Lentis, also known as familial ectopia lentis, is related to craniosynostosis with ectopia lentis and ectopia lentis 2, isolated, autosomal recessive. An important gene associated with Isolated Ectopia Lentis is FBN1 (Fibrillin 1), and among its related pathways/superpathways are Metabolism of proteins and Phospholipase-C Pathway. The drugs Midazolam and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include eye and bone, and related phenotypes are joint stiffness and ectopia lentis