Interstitial Lung and Liver Disease (ILLD)

Interstitial Lung and Liver Disease, also known as severe early-onset pulmonary alveolar proteinosis due to mars deficiency, is related to interstitial lung disease and infantile liver failure syndrome 2. An important gene associated with Interstitial Lung and Liver Disease is MARS1 (Methionyl-TRNA Synthetase 1), and among its related pathways/superpathways is tRNA Aminoacylation. Affiliated tissues include liver and lung, and related phenotypes are hypothyroidism and hypotonia