Immunodeficiency 38 with Basal Ganglia Calcification (IMD38)

Immunodeficiency 38 with Basal Ganglia Calcification, also known as mendelian susceptibility to mycobacterial diseases due to complete isg15 deficiency, is related to systemic lupus erythematosus and myositis. An important gene associated with Immunodeficiency 38 with Basal Ganglia Calcification is ISG15 (ISG15 Ubiquitin Like Modifier), and among its related pathways/superpathways is Pathways of nucleic acid metabolism and innate immune sensing. Affiliated tissues include bone and skin, and related phenotypes are seizure and lymphadenopathy