Ichthyosis, X-Linked (XLI)

Ichthyosis, X-Linked, also known as x-linked ichthyosis, is related to chondrodysplasia punctata syndrome and multiple sulfatase deficiency. An important gene associated with Ichthyosis, X-Linked is STS (Steroid Sulfatase), and among its related pathways/superpathways is Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation. The drug Isotretinoin has been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are ichthyosis and hyperkeratosis