Ichthyosis, also known as ichthyoses, is related to ichthyosis, congenital, autosomal recessive 4b and ichthyosis, congenital, autosomal recessive 1, and has symptoms including trichorrhexis invaginata An important gene associated with Ichthyosis is ALOXE3 (Arachidonate Lipoxygenase 3), and among its related pathways/superpathways are Keratinization and Prostaglandin 2 biosynthesis and metabolism FM. The drugs Ustekinumab and Copper have been mentioned in the context of this disorder. Affiliated tissues include skin and neutrophil, and related phenotypes are homeostasis/metabolism and growth/size/body region