Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy (EOHSEP)

Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy, also known as hypertension, early-onset, autosomal dominant, with exacerbation in pregnancy, is related to hypertension due to gain-of-function mutations in the mineralocorticoid receptor, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy is NR3C2 (Nuclear Receptor Subfamily 3 Group C Member 2). The drugs Indapamide and Amlodipine have been mentioned in the context of this disorder.