Hereditary Spastic Paraplegia 49 (SPG49)

Hereditary Spastic Paraplegia 49, also known as autosomal recessive spastic paraplegia type 49, is related to spastic paraplegia 20, autosomal recessive and spastic ataxia, and has symptoms including gait ataxia An important gene associated with Hereditary Spastic Paraplegia 49 is TECPR2 (Tectonin Beta-Propeller Repeat Containing 2), and among its related pathways/superpathways is trans-Golgi Network Vesicle Budding. Related phenotypes are nervous system and cellular