Hemolytic Anemia, Nonspherocytic, Due to Glucose Phosphate Isomerase Deficiency, is also known as hemolytic anemia due to glucophosphate isomerase deficiency. An important gene associated with Hemolytic Anemia, Nonspherocytic, Due to Glucose Phosphate Isomerase Deficiency is GPI (Glucose-6-Phosphate Isomerase). Affiliated tissues include bone marrow and bone.