High-Grade B-Cell Lymphoma Double-Hit/triple-Hit

High-Grade B-Cell Lymphoma Double-Hit/triple-Hit, also known as high grade b-cell lymphoma with myc and/ or bcl2 and/or bcl6 rearrangement, is related to lymphoma aids related and intravascular large b-cell lymphoma. An important gene associated with High-Grade B-Cell Lymphoma Double-Hit/triple-Hit is BCL6 (BCL6 Transcription Repressor), and among its related pathways/superpathways are TNFR1 Pathway and Toll-like receptor signaling pathway. The drugs Azacitidine and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and bone, and related phenotypes are neoplasm and cellular