High Grade Ependymoma

High Grade Ependymoma, also known as malignant ependymoma, is related to subependymal glioma and glial tumor, and has symptoms including headache, nausea and seizures. An important gene associated with High Grade Ependymoma is NF2 (NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor), and among its related pathways/superpathways are Neuroscience and PKMTs methylate histone lysines. The drugs Lenograstim and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and brain, and related phenotypes are Increased proliferation and Decreased p24 protein expression