Gastrointestinal Stromal Tumor (GIST)

Alias:
Gist
Gastrointestinal Stromal Sarcoma
Gastrointestinal Stromal Tumor, Familial
Gastrointestinal Stromal Tumors
Paraganglioma and Gastric Stromal Sarcoma
Stromal Tumour of Gastrointestinal Tract
Stromal Tumor of Gastrointestinal Tract
Gastrointestinal Stromal Neoplasm
Cancer, Gastrointestinal Stromal
Gastrointestinal Stromal Tumour
Plexosarcoma
Gant
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基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
胃肠道间质瘤,也称为gist,与副神经节瘤、胃间质肉瘤和间质细胞瘤有关。与胃肠道间质瘤相关的重要基因是KIT(KIT原癌基因,受体酪氨酸激酶),其相关通路/超级通路包括ERK信号通路和信号转导通路。在该疾病的背景下提到了依维莫司和埃索美拉唑。附属组织包括小肠和结肠,相关表型为胃的肉瘤和肿瘤
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
常显
孩童期
1-5/10000
124
2003
299

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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