Gingival Disease

Gingival Disease, also known as gum disease, is related to histiocytosis and gingival overgrowth, and has symptoms including halitosis, snoring and tenderness of gums. An important gene associated with Gingival Disease is MMP8 (Matrix Metallopeptidase 8), and among its related pathways/superpathways are Innate Immune System and Infectious disease. The drugs Zinc cation and Sodium fluoride have been mentioned in the context of this disorder. Affiliated tissues include bone and heart, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and homeostasis/metabolism