Glanzmann Thrombasthenia 1 (GT1)

Glanzmann血小板无力症1型(来自ICD-11)

别称:

Glanzmann Thrombasthenia

Glanzmann's Thrombasthenia

Deficiency of Platelet Fibrinogen Receptor

Platelet Glycoprotein Iib-Iiia Deficiency

Thrombasthenia of Glanzmann and Naegeli

Bdplt2

Deficiency of Glycoprotein Complex Iib-Iiia

Glycoprotein Complex Iib-Iiia Deficiency

Platelet Fibrinogen Receptor Deficiency

Glycoprotein Iib/iiia Defect

Thrombasthenia

Gt1

Hereditary Hemorrhagic Thrombasthenia

Bleeding Disorder, Platelet-Type, 2

Deficiency of Gp Iib-Iiia Complex

Platelet-Type Bleeding Disorder 2

Bleeding Disorder Platelet-Type 2

Glanzmann Thrombasthenia, Type a

Gp Iib-Iiia Complex Deficiency

Glanzmann-Naegeli Disorder

Hereditary Thrombasthenia

Thrombocytasthenia

Glanzmann Disease

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基础信息

疾病表征

基因 & 突变

靶点药物

疾病模型

文献报道

Glanzmann Thrombasthenia 1，也称为Glanzmann血小板无力症1，与Glanzmann血小板无力症2和出血障碍，血小板型，24有关。与Glanzmann Thrombasthenia 1相关的基因是ITGA2B（整合素亚基α2b），其相关通路/超级通路包括整合素通路和PI3K-Akt信号通路。在该疾病的背景下，已提到的药物有氟达拉滨和环磷酰胺。附属组织包括皮肤和扁桃体，相关表型为延长的出血时间和自发，复发性鼻出血。

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