Global Developmental Delay, Lung Cysts, Overgrowth, and Wilms Tumor, also known as glow syndrome, is related to sickle cell disease and deficiency anemia. An important gene associated with Global Developmental Delay, Lung Cysts, Overgrowth, and Wilms Tumor is DICER1 (Dicer 1, Ribonuclease III). Affiliated tissues include lung and skin, and related phenotypes are macrocephaly and frontal bossing