Familial Acute Necrotizing Encephalopathy, also known as recurrent acute necrotizing encephalopathy, is related to encephalitis, acute, infection-induced 12 and acute necrotizing encephalitis. An important gene associated with Familial Acute Necrotizing Encephalopathy is RANBP2 (RAN Binding Protein 2). Affiliated tissues include thalamus and brain, and related phenotypes are coma and acute encephalopathy