Familial Cold Autoinflammatory Syndrome 3 (FCAS3)

Familial Cold Autoinflammatory Syndrome 3, also known as familial atypical cold urticaria, is related to familial cold autoinflammatory syndrome and familial mediterranean fever. An important gene associated with Familial Cold Autoinflammatory Syndrome 3 is PLCG2 (Phospholipase C Gamma 2). The drugs Lisinopril and protease inhibitors have been mentioned in the context of this disorder. Affiliated tissues include skin and b cells, and related phenotypes are erythema and pruritus