Factor Xii Deficiency (FA12D)

Factor Xii Deficiency, also known as hageman factor deficiency, is related to congenital factor xii deficiency and angioedema, hereditary, 3. An important gene associated with Factor Xii Deficiency is F12 (Coagulation Factor XII), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Diseases of hemostasis. The drugs Kallikreins and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include whole blood and brain, and related phenotypes are prolonged partial thromboplastin time and reduced factor xii activity