Endodermal Sinus Tumor

Endodermal Sinus Tumor, also known as yolk sac tumor, is related to childhood endodermal sinus tumor and testicular germ cell tumor. An important gene associated with Endodermal Sinus Tumor is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Metabolism of proteins and NF-kappaB Signaling. The drugs Picropodophyllin and Bleomycin have been mentioned in the context of this disorder. Affiliated tissues include testis and ovary, and related phenotypes are Increased shRNA abundance (Z-score > 2) and digestive/alimentary