Donohue Syndrome (LEPRCH)

Donohue Syndrome, also known as leprechaunism, is related to pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities and hypertrichosis, and has symptoms including elfin facies and female breast hyperplasia. An important gene associated with Donohue Syndrome is INSR (Insulin Receptor), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. Affiliated tissues include skin and heart, and related phenotypes are hyperkeratosis and postnatal growth retardation