Dihydropyrimidine Dehydrogenase Deficiency (DPYDD)

Dihydropyrimidine Dehydrogenase Deficiency, also known as familial pyrimidinemia, is related to dihydropyrimidinase deficiency and rectum cancer, and has symptoms including lethargy and seizures. An important gene associated with Dihydropyrimidine Dehydrogenase Deficiency is DPYD (Dihydropyrimidine Dehydrogenase), and among its related pathways/superpathways are Metabolism and Metapathway biotransformation Phase I and II. The drugs Capecitabine and Fluorouracil have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are uraciluria and reduced dihydropyrimidine dehydrogenase level