Diabetes and Deafness, Maternally Inherited (MIDD)

母系遗传糖尿病和耳聋(来自ICD-11)

别称:

Midd

Noninsulin-Dependent Diabetes Mellitus with Deafness

Diabetes-Deafness Syndrome Maternally Transmitted

Maternally-Inherited Diabetes and Hearing Loss

Maternally-Inherited Diabetes and Deafness

Maternally Inherited Diabetes and Deafness

Diabetes Mellitus, Type Ii, with Deafness

Ballinger-Wallace Syndrome

Mitochondrial Diabetes

Niddm with Deafness

Diabetes-Deafness Syndrome, Maternally Transmitted

Maternally Transmitted Diabetes-Deafness Syndrome

Mitochondrial Inherited Diabetes and Deafness

加入收藏

基础信息

疾病表征

基因 & 突变

靶点药物

疾病模型

文献报道

糖尿病和耳聋，母系遗传，也被称为MIDD，与线粒体肌病、脑病、乳酸酸中毒和类似中风的发作以及Kearns-Sayre综合症有关。与糖尿病和耳聋，母系遗传有关的重要基因是MT-TE（线粒体编码的TRNA-Glu（GAA/G））。在该疾病的背景下，已提到的药物有6-羟基-2,5,7,8-四甲基-2-羧基chroman-2-酸和保护剂。附属组织包括眼睛和视网膜，相关表型包括便秘和2型糖尿病。

查看原文参与反馈