Cryopyrin-Associated Periodic Syndrome, also known as cryopyrinopathy, is related to cinca syndrome and familial cold autoinflammatory syndrome 1. An important gene associated with Cryopyrin-Associated Periodic Syndrome is NLRP3 (NLR Family Pyrin Domain Containing 3), and among its related pathways/superpathways are Toll-Like receptor Signaling Pathways and IL1 and megakaryocytes in obesity. The drugs Plasminogen and Ambrisentan have been mentioned in the context of this disorder. Affiliated tissues include skin and spinal cord, and related phenotype is Increased shRNA abundance (Z-score > 2).