Currarino Syndrome, also known as currarino triad, is related to holoprosencephaly and sacral defect with anterior meningocele, and has symptoms including chronic constipation An important gene associated with Currarino Syndrome is MNX1 (Motor Neuron And Pancreas Homeobox 1). Affiliated tissues include spinal cord and bone, and related phenotypes are aplasia/hypoplasia of the sacrum and sacrococcygeal teratoma