Cornelia De Lange Syndrome 4 with or Without Midline Brain Defects (CDLS4)

Cornelia De Lange Syndrome 4 with or Without Midline Brain Defects, also known as cornelia de lange syndrome 4, is related to trichorhinophalangeal syndrome and trichorhinophalangeal syndrome, type i. An important gene associated with Cornelia De Lange Syndrome 4 with or Without Midline Brain Defects is RAD21 (RAD21 Cohesin Complex Component), and among its related pathways/superpathways are Cell Cycle, Mitotic and EML4 and NUDC in mitotic spindle formation. Affiliated tissues include brain and heart, and related phenotypes are cleft palate and hemivertebrae