Canavan Disease (CAND)

Canavan Disease, also known as aspartoacylase deficiency, is related to leukodystrophy and hypotonia, and has symptoms including opisthotonus An important gene associated with Canavan Disease is ASPA (Aspartoacylase), and among its related pathways/superpathways are Aspartate and asparagine metabolism and Alanine and aspartate metabolism. The drugs Levetiracetam and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include brain and skin, and related phenotypes are macrocephaly and eeg abnormality