Conn's Syndrome

康尼综合症(来自翻译大模型)

别称:

Hyperaldosteronism

Cushing Syndrome

Primary Hyperaldosteronism

Primary Aldosteronism

Hypercortisolism

Cushing's Syndrome

Cushing Disease

Conn Syndrome

Pituitary Corticotroph Micro-Adenoma

Pituitary-Dependent Cushing Syndrome

Corticotroph Pituitary Adenoma

Pituitary Acth Hypersecretion

Hyperadrenocorticism

Ectopic Acth - [adrenocorticotropic Hormone] Secretion Causing Cushing Syndrome

Primary Aldosteronism Due to Bilateral Adrenal Hyperplasia

Ectopic Acth - [adrenocorticotropic Hormone] Secretion

Cushing Syndrome Secondary to Ectopic Acth-Secretion

Primary Aldosteronism Due to Adrenal Hyperplasia

Pituitary-Dependant Hypercortisolism Disorder

Hypercortisolism Due to Nonpituitary Tumour

Pituitary-Dependant Cushing Syndrome

Pituitary-Dependant Hypercortisolism

Corticoadrenal Hypersecretion

Adrenal Gland Hyperfunction

Pituitary Cushing Syndrome

Adrenal Cushing's Syndrome

Adrenal Cortical Adenoma

Ectopic Cushing Syndrome

Idiopathic Aldosteronism

Cortisol Hypersecretion

Acth Syndrome, Ectopic

Aldosteronism Primary

Cushing Syndrome Nos

Cushing's Disease

Aldosteronism

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基础信息

疾病表征

基因 & 突变

靶点药物

疾病模型

文献报道

康氏综合症，也被称为醛固酮增多症，与异位库欣综合症和色素性结节性肾上腺皮质病、原发性1型有关，症状包括库欣面容。与康氏综合症相关的重要基因是USP8（泛素特异性肽酶8），其相关通路/超级通路包括传染病和代谢。在该疾病的背景下，已提到的药物有溴隐亭和利拉鲁肽。附属组织包括垂体和肾上腺，相关表型为循环皮质醇水平增加和地塞米松抑制试验中悖论性皮质醇分泌增加。

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