Cleft Palate, Psychomotor Retardation, and Distinctive Facial Features (CPRF)

Cleft Palate, Psychomotor Retardation, and Distinctive Facial Features, is also known as palatal anomalies-widely spaced teeth-facial dysmorphism-developmental delay syndrome. An important gene associated with Cleft Palate, Psychomotor Retardation, and Distinctive Facial Features is KDM1A (Lysine Demethylase 1A). Affiliated tissues include cerebellum and brain, and related phenotypes are hypotonia and global developmental delay