Cleft Palate, Cardiac Defect, Genital Anomalies, and Ectrodactyly (ACFS)

Cleft Palate, Cardiac Defect, Genital Anomalies, and Ectrodactyly, also known as acrocardiofacial syndrome, is related to cleft palate, isolated and split-hand/foot malformation 1. Affiliated tissues include heart and colon, and related phenotypes are intellectual disability and feeding difficulties in infancy