Cloacal Exstrophy

Cloacal Exstrophy, also known as omphalocele-cloacal exstrophy-imperforate anus-spinal defect syndrome, is related to bladder exstrophy-epispadias-cloacal exstrophy complex and bladder exstrophy. An important gene associated with Cloacal Exstrophy is GKAP1 (G Kinase Anchoring Protein 1), and among its related pathways/superpathways are Metabolism of steroids and Metabolism of steroid hormones. Affiliated tissues include kidney and uterus, and related phenotypes are vesicoureteral reflux and hypoplasia of penis