Coloboma of Eye Lens

Coloboma of Eye Lens is related to microphthalmia, syndromic 6 and nystagmus 3, congenital, autosomal dominant. An important gene associated with Coloboma of Eye Lens is ABCB6 (ATP Binding Cassette Subfamily B Member 6 (Langereis Blood Group)), and among its related pathways/superpathways are Mesodermal commitment pathway and Ectoderm differentiation. Affiliated tissues include eye and retina, and related phenotype is Decreased human papilloma virus 16 (HPV16) pseudovirus infection.