Chronic Myelomonocytic Leukemia (CMML)

Chronic Myelomonocytic Leukemia, also known as cmml, is related to juvenile myelomonocytic leukemia and immunodeficiency 21, and has symptoms including fatigue, fever and night sweats. An important gene associated with Chronic Myelomonocytic Leukemia is ETV6 (ETS Variant Transcription Factor 6), and among its related pathways/superpathways are ERK Signaling and Akt Signaling. The drugs Lenograstim and Omacetaxine mepesuccinate have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and myeloid, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism