Chronic Ulcer of Skin, also known as chronic wounds, is related to ulcer of lower limbs and venous insufficiency. An important gene associated with Chronic Ulcer of Skin is FGF2 (Fibroblast Growth Factor 2), and among its related pathways/superpathways are Innate Immune System and GPCR Pathway. The drugs Laxatives and Gastrointestinal Agents have been mentioned in the context of this disorder. Affiliated tissues include skin and bone marrow, and related phenotypes are homeostasis/metabolism and cardiovascular system