Chronic Lacrimal Gland Enlargement, also known as chronic enlargement of lacrimal gland, is related to acute serous otitis media and middle ear cholesterol granuloma. An important gene associated with Chronic Lacrimal Gland Enlargement is PRTN3 (Proteinase 3), and among its related pathways/superpathways is C-MYB transcription factor network. Related phenotype is Reduced mammosphere formation.