Cholestasis-Lymphedema Syndrome (LCS)

Cholestasis-Lymphedema Syndrome, also known as aagenaes syndrome, is related to hereditary lymphedema i and hereditary lymphedema, and has symptoms including icterus An important gene associated with Cholestasis-Lymphedema Syndrome is LCS1 (Lymphedema-Cholestasis Syndrome 1), and among its related pathways/superpathways are Metabolism of steroids and Synthesis of bile acids and bile salts. Affiliated tissues include skin and liver, and related phenotypes are nausea and vomiting and hepatomegaly