Bruxism, also known as sleep-related bruxism, is related to rett syndrome and sleep disorder, and has symptoms including sleep disturbances, snoring and toothache. An important gene associated with Bruxism is MECP2 (Methyl-CpG Binding Protein 2), and among its related pathways/superpathways are Beta-Adrenergic Signaling and Neuroscience. The drugs Acetylcholine and Trazodone have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle and bone, and related phenotypes are shRNA abundance <= 50% and nervous system