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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
罕见病
Bipolar Disorder
Alias:
Depression, Bipolar
Bipolar Depression
Manic Disorder
Manic Bipolar Affective Disorder
Bipolar Disorder Manic Phase
Bipolar Affective Psychosis
Major Affective Disorder 1
Bipolar Affective Disorder
Major Affective Disorder 2
Manic Depressive Disorder
Bipolar Spectrum Disorder
Manic Bipolar I Disorder
Manic Depressive Illness
Major Affective Disorder
Depressive-Manic Psych.
Bipolar Disorder, Mixed
Mixed Bipolar Disorder
Depression Bipolar
Manic Depression
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基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
双相情感障碍,也被称为抑郁、双相,与双相情感障碍I型和重度抑郁症有关。与双相情感障碍相关的重要基因是DISC2(精神分裂症2型的破坏),其相关通路/超级通路包括化学突触间的传递和神经科学。在该疾病的背景下提到了利培酮和阿塞那平。相关组织包括大脑和前额叶皮层,相关表型为shRNA丰度增加(Z分数>2)和神经系统。
Related ID:
MALACARDS:BPL003
MESH:D001714
Basic Information
Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
未知
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75
903
3
BPL003
Medical Symptom
#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available
Gene & Mutation
#
Gene
Function
Score
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
No data available
Disease Model
Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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