B-Lymphoblastic Leukemia/lymphoma with Iamp21

B-Lymphoblastic Leukemia/lymphoma with Iamp21, also known as intrachromosomal amplification of chromosome 21, is related to down syndrome and childhood acute lymphocytic leukemia. An important gene associated with B-Lymphoblastic Leukemia/lymphoma with Iamp21 is P2RY8 (P2Y Receptor Family Member 8), and among its related pathways/superpathways are NF-kappaB Signaling and Prion disease pathway. The drugs Fludarabine and Levetiracetam have been mentioned in the context of this disorder. Affiliated tissues include myeloid, and related phenotypes are Reduced mammosphere formation and Synthetic lethal with vaccinia virus (VACV) infection