Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Alias:
Blastic Nk-Cell Lymphoma
Cd4+/cd56+ Hematodermic Neoplasm
Bpdcn
Agranular Cd4+ Cd56+ Hematodermic Neoplasm/tumor
Agranular Cd4+ Natural Killer Cell Leukemia
Agranular Cd4+/cd56+ Haematodermic Neoplasm
Lymphoblastoid Variant of Nk-Cell Lymphoma
Blastic Natural Killer Leukemia/lymphoma
Natural Killer Cell Leukemia/lymphoma
Blastic Nk-Cell Leukaemia/​lymphoma
Monomorphic Nk-Cell Lymphoma
Agranular Cd4+ Nk Leukaemia
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基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
急性髓系白血病,也称为急性单核细胞白血病,与血液系统癌症和白血病有关。与急性髓系白血病相关的重要基因是IL3RA(白细胞介素3受体亚基α),其相关通路/超级通路包括先天免疫系统和NF-κB信号通路。在该疾病的背景下提到了药物阿糖胞苷和长春新碱。相关组织包括髓系和骨髓,相关表型为免疫系统和造血系统。
Related ID:
ICD11:783045723

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
老年人
1-5/10000
20
173
--

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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