Azoospermia, also known as infertility due to azoospermia, is related to male infertility with azoospermia or oligozoospermia due to single gene mutation and male infertility. An important gene associated with Azoospermia is MEIOB (Meiosis Specific With OB-Fold), and among its related pathways/superpathways are Gene Silencing by RNA and Primary ovarian insufficiency. The drugs Metformin and Chorionic Gonadotropin have been mentioned in the context of this disorder. Affiliated tissues include testis and bone marrow, and related phenotypes are endocrine/exocrine gland and cellular