Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2a

Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2a, also known as limb-girdle muscular dystrophy due to calpain deficiency, is related to muscular dystrophy, limb-girdle, autosomal recessive 1 and cardiomyopathy, familial hypertrophic, 1. An important gene associated with Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2a is CAPN3 (Calpain 3), and among its related pathways/superpathways are Cardiac conduction and Extracellular matrix organization. Affiliated tissues include heart and skeletal muscle, and related phenotypes are generalized muscle weakness and hyperlordosis