Autosomal Recessive Congenital Ichthyosis (LI)

Autosomal Recessive Congenital Ichthyosis, also known as lamellar ichthyosis, is related to ichthyosis, congenital, autosomal recessive 1 and ichthyosis, congenital, autosomal recessive 4a. An important gene associated with Autosomal Recessive Congenital Ichthyosis is ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type), and among its related pathways/superpathways are Keratinization and Prostaglandin 2 biosynthesis and metabolism FM. The drugs Ustekinumab and Bezafibrate have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are ichthyosis and abnormality of the nail