Aortic Disease

Aortic Disease, also known as disorder of the aorta, is related to aortic dissection and loeys-dietz syndrome 1. An important gene associated with Aortic Disease is FBN1 (Fibrillin 1), and among its related pathways/superpathways are MicroRNAs in cardiomyocyte hypertrophy and TGF-beta receptor signaling activates SMADs. The drugs Propofol and Sevoflurane have been mentioned in the context of this disorder. Affiliated tissues include heart and smooth muscle, and related phenotype is muscle.