Arteriolosclerosis is related to calciphylaxis and atherosclerosis susceptibility. An important gene associated with Arteriolosclerosis is C3 (Complement C3), and among its related pathways/superpathways are Neuroscience and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). Affiliated tissues include smooth muscle and kidney, and related phenotypes are growth/size/body region and muscle