Ankyloblepharon-Ectodermal Defects-Cleft Lip/palate (AEC)

Ankyloblepharon-Ectodermal Defects-Cleft Lip/palate, also known as hay-wells syndrome, is related to cleft lip/palate and cleft lip, and has symptoms including pachyonychia. An important gene associated with Ankyloblepharon-Ectodermal Defects-Cleft Lip/palate is TP63 (Tumor Protein P63), and among its related pathways/superpathways are Keratinization and Head and neck squamous cell carcinoma. Affiliated tissues include skin and eye, and related phenotypes are wide nasal bridge and coarse hair.