Anhidrosis, also known as hypohidrosis, is related to insensitivity to pain, congenital, with anhidrosis and neuropathy, hereditary sensory and autonomic, type v, and has symptoms including hyperthermia and increased sweating. An important gene associated with Anhidrosis is ITPR2 (Inositol 1,4,5-Trisphosphate Receptor Type 2), and among its related pathways/superpathways are Innate Immune System and GPCR Pathway. Affiliated tissues include skin and spinal cord, and related phenotypes are Decreased viability and Increased human cytomegalovirus (HCMV) strain AD169 replication